CaspBase.org
Dr. Bob Grinshpon developed the CaspBase, a curated database with over 2,000 sequences of caspase proteins from over 360 taxa. Bob’s paper describing the database is now in press at Protein Science and is titled: The CaspBase: A curated database for evolutionary biochemical studies of caspase functional divergence and ancestral sequence inference.
Using data from the CaspBase, we describe the utility of the database by analyzing levels of sequence conservation among caspase homologs, and we discuss how the CaspBase lends itself to evolutionary biochemistry and ancestral protein reconstruction (APR) analysis of common caspase ancestral proteins.
The database is available at CaspBase.org
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