Tag Archives: News

ASBMB Today Interview with Dr. Melvin Thomas III

ASBMB_Today_ThomasMelvin’s recent JBC paper was the subject of this recent interview in ASBMB Today. Melvin showed that an evolutionarily conserved phosphorylation site in caspases uses a common allosteric¬† network to decrease the activity of caspase-3. A mutation in mammalian caspase-3 introduces a kill-switch into the enzyme so that it is turned off when the site is phosphorylated.

Melvin’s paper was published recently in the Journal of Biological Chemistry.

Comments Off on ASBMB Today Interview with Dr. Melvin Thomas III

Filed under News